Supplement for brain health

Phosphatidylserine

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Phosphatidylserine
Identifiers
CAS number	8002-43-5
PubChem	445141
Properties
Molecular formula	C13H24NO10P
Molar mass	385.304
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox references

Phosphatidylserine (abbreviated Ptd-L-Ser, or PS) is a phospholipid component, usually kept on the inner-leaflet, the cytosolic side, of cell membranes by an enzyme called translocase.

Contents 1 Health Benefits 1.1 Memory and Cognition 1.2 Sports Nutrition 1.3 Attention-deficit hyperactivity disorder 2 Safety 3 Dietary Sources 4 Applications 4.1 Research 4.2 Tumor 5 References 6 External links

Health Benefits

Memory and Cognition

Early studies of phosphatidylserine distilled the chemical from bovine brain. Because of concerns about Bovine Spongiform Encephalopathy, however, modern studies and commercially available products are made from soybeans. The fatty acids attached to the serine in the soy product are not identical to those in the bovine product, which is also impure. However, preliminary studies indicate that the soy product is at least as effective as that of bovine origin. ^[1][2]

On May 13, 2003, the U.S. Food and Drug Administration stated "based on its evaluation of the totality of the publicly available scientific evidence, the agency concludes that there is not significant scientific agreement among qualified experts that a relationship exists between phosphatidylserine and reduced risk of dementia or cognitive dysfunction." FDA did, however give "qualified health claim" status to phosphatidylserine, stating that "Consumption of phosphatidylserine may reduce the risk of dementia in the elderly" and "Consumption of phosphatidylserine may reduce the risk of cognitive dysfunction in the elderly".

Sports Nutrition

Phosphatidylserine has been demonstrated to speed up recovery, prevent muscle soreness, improve well-being, and might possess ergogenic properties in athletes involved in cycling, weight training and endurance running. PS has been reported to be an effective supplement for combating exercise-induced stress by blunting the exercise-induced increase in cortisol levels.^[3] PS supplementation promotes a desirable hormonal balance for athletes and might attenuate the physiological deterioration that accompanies overtraining and/or overstretching.^[4] In recent studies, PS has been shown to enhance mood in a cohort of young people during mental stress and to improve accuracy during tee-off by increasing the stress resistance of golfers.^[5]

Attention-deficit hyperactivity disorder

First pilot studies indicate that PS supplementation might be beneficial for children with attention-deficit hyperactivity disorder.^[6][7]

Taken from WIKIPEDIA